Protein folded into a five petalled rose.

Physical Methods and Life Sciences

The White Rose Doctoral Training Centre (DTC)

Universities of Leeds and Sheffield

No further applications are being accepted for this course.

List of project options for 2008-9

Image of fat cells from project 6.
  1. Atomic Force Microscopy Study of Cellular Interactions Relevant to Biofilm Formation
  2. Control of Cell Adhesion by Control of Polymer Swelling in Stumulus Responsive Materials
  3. Mass Spectrometry in the Biomolecular Sciences
  4. How Do Enzymes Pull Apart Proteins?
  5. Inhibition of Protein-Protein Interactions with Small Molecule Probes
  6. Fat and Ultrasound
  7. NMR-Based Profiling of Oxidative Stress Markers of Ovarian Follicular Fluid and Plasma
  8. Modelling of Alpha-Helical Coiled-Coils: Can the Two Limbs Slide?
  9. Coarse-Grained Theory of Protein Dynamics
  10. Enzymes Involved in DNA Replication and Repair
  11. New Drugs for 'Superbugs'
  12. Nanoscale Patterning of Membrane Proteins and Enzymes
  13. A Novel Technique to Examine the Structure of Engineered Tissues
  14. Site-Specific Photo-Crosslinking as a Tool in Systems Biology
  15. Polymers Responsive to Biological Stimuli
  16. Substrate Recognition and Function of Alkyltransferase-Like Protein Atl1
  17. Application of Computer-Aided Drug Design to Combat Bacterial Resistance Computer aided design of drug molecules, from project 19.
  18. Precision Magnetometry
  19. Real-Time Molecular Mapping of Bacterial Surfaces with High Speed Atomic Force Microscopy
  20. Electron and Proton Transfer
  21. Directed Evolution of Enzymes for Synthetic Organic Chemistry
  22. Chemical Genetics of Membrane Proteins
  23. Molecular Nano-Technology and Nano-Engineering
  24. Spectroscopic Analysis at THz Frequencies of Acoustically-Positioned Biomolecules
  25. NMR-Based Metabonomics: A Novel Approach to Studying Complex Disease in Children and Young Adults
  26. Biophotonics and Dental Materials: Photo-Activation Processes in Skeletal Minerals for the Treatment of Dental Cavities
  27. Biomimetic Self-Assembled Helical Porous Channels
  28. Bacterial Polyesters - Processing and Deformation Mechanism of Environmentally Friendly Plastics
  29. Synthesis and Study of High Loading Site Specific Drug Delivery Systems
  30. Construction of Phosphoinositols and Glycoconjugates as Molecular Probes
  31. Influence on Cell Behaviour of Protein Adsorption to Surfaces
  32. Application of Stable Analogues of Phosphohistidine to the Study of Cell Signalling Pathways
  33. Analysis of Three-Dimensional Structure of DNA or Protein Ligand Interactions
  34. Bone and Cartilage Tissue Engineering, Mechanical Stimulation and Scaffold Design
  35. Rapid Discovery of Intelligent Molecular Probes for Chemical Intervention of bBological Systems
  36. Structure and Function in the AAA+ Protein Super-Family
  37. Biomimetic Membranes: from Protein Immobilization to Gene and Drug Delivery
  38. Biological Prediction, Machine Learning and Molecular Networks
  39. Identification of Arginine Methylation of Nuclear Protein Complexes using Mass Spectrometry
  40. Dynamic Heterogeneity in the Heart
  41. Development of a Convenient Mechanical Conditioning Device for Tendon or Ligament Tissue Engineering
  42. NMR Studies of Articular Cartilage
  43. DNA-Protein Interactions at the Single Molecule Level Observed with Atomic Force Microscopy
  44. Oligonucleotide-Based Inactivators of MGMT - Design and Delivery
  45. Synthesis and Molecular Biology to Regulate Nonsense-Mediated Decay
  46. Fibroblast Growth Factor Receptors (FGFR) as Anti-Cancer Drug Targets. From Bench to Bedside Inhibitor docked with FGFR molecule, from project 46.
  47. Treating the Untreatable : Harnessing Chemistry, Fluorescence and Zebrafish to Battle Motor Neurone Disease (MND)
  48. Single Molecule Investigation of Viral RNA Condensation and Packaging
  49. Unravelling the Molecular Structure of the Bacterial Cell Wall
  50. Biophysical Model of Arrhythmias in the Infarcted Human Heart
  51. The Biophysics of Cell Membranes
  52. Molecular Mechanism of an ADP-Dependent Phosphorylation Event

You can download the complete listing as a PDF file through the link below:

Current projects list.
(PDF, 213kB)

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